Axon Axopatch 200B with a headstage, Axon Digidata 1550B Digitizer, and pCLAMP 11

Internal part number SM100021-1550B

• Fully Functional
• Serviced & in Stock
• Current Model
• Good cosmetic condition
• Technical sales consultation available
• 60 DAYS INTERNATIONAL WARRANTY
• Includes remote instrument setup and training session 

Here is what you will receive:

• Axopatch 200B Main Amplifier Unit
• 1x CV 203BU Headstage
• Axon Digidata 1550B Digitizer
• Headstage interface cable
• USB 2.0 cable for digitizer-to-PC connection
• Power supply and signal breakout cables
• Data Acquisition PC with pCLAMP 11 license dongle

Patch Clamp Amplifier Configuration:

• Model: Axon Instruments Axopatch 200B Microelectrode Amplifier
• Included Headstage: 1x CV 203BU Headstage (single-channel)
• Compatible with low-capacitance pipette holders
• Designed for ultra-low-noise performance

Key Features:

• Dual mode operation: Voltage Clamp & Current Clamp
• Fast capacitive and series resistance compensation
• Integrated low-pass Bessel filter (selectable cutoff frequencies)
• Scaled analog outputs for real-time signal monitoring (IMon, VMon, Command)
• Capacitive feedback technology for stable gigaseal recordings
• Precision Tool for single-channel, whole-cell, and excised patch configurations, particularly in neuronal or cardiac electrophysiology.

Data Digitizer Configuration:

• Model: Axon Digidata 1550B Low-Noise Data Acquisition System
• Interface: USB 2.0 (High-Speed)
• Sampling Rate: Up to 500 kHz per channel
• Resolution: 16-bit A/D and D/A conversion
• Configuration Options:

- 8 analog input channels

- 4 analog output channels

- 16 digital I/O lines (8 in / 8 out)

• Low-Noise Design:
• Engineered with separate A/D and D/A converters for reduced crosstalk
• Enhanced shielding for minimal digitizer-induced noise
• Digital synchronization port for integration with other devices (e.g., imaging or stimulation hardware)
• Next-Gen Capabilities: Enables high-speed, high-precision data acquisition, essential for capturing fast biological events or high-frequency stimuli.

Data Acquisition PC & Software:

• PC: Modern computer system optimized for electrophysiology workflows
• Software:
• pCLAMP 10.x or later
• Includes Clampex (acquisition), Clampfit (analysis), and AxoScope
• USB license dongle and full driver support for the amplifier and digitizer

Key Software Features:

• Programmable voltage/current protocols
• Seal test, series resistance compensation
• Leak subtraction and stimulus waveform design
• Online & offline filtering, peak analysis, and event detection

System Integration & Use Case Highlights

• With exceptional low-noise characteristics and high-speed sampling, it is suitable for:
• Precise voltage control and current measurement
• Real-time stimulus-response recording
• Integration with optical systems (e.g., for optogenetics or calcium imaging)
• Complex multi-phase protocols with digital/analog synchronization
• Perfect for: Ion channel research, synaptic physiology, membrane biophysics, cardiac myocyte studies, and neuropharmacology

Common Applications:

• Whole-cell patch clamp (voltage- and current-clamp)
• Single-channel recordings
• Synaptic current analysis
• Drug-response assays
• Action potential detection
• Optogenetics (via synchronized digital outputs)

Optional Accessories (For an additional fee):

• Additional headstages
• Pipette holders with integrated Ag/AgCl electrodes
• Faraday cage and vibration isolation table
• Perfusion systems or stimulus isolators
• High-resolution cameras or light sources (for synchronized imaging)
• Temperature controllers or in-line solution heaters

Why do so many customers choose to order from us?

Our Advantage

• We have experience servicing and repairing these instruments.
• This instrument goes through all the described service steps before shipping.  see the questions section below  
• We offer detailed photos of the instruments you buy.
• We are an approved pre-owned equipment vendor to many large US, Canadian, and EU Universities.
• We are an approved pre-owned equipment vendor to many Fortune 500 US and International Biopharma companies. 
• Technical sales consultation available
• Remote installation and instrument operation training may be available.
• On-site installation may be available in the Boston Area (New England area)
• US or International shipping is no problem (see the shipping tab on how we pack and feel at ease)

Our Guarantee

• Warranty
• An extended warranty may be available
• You get after-sales technical support
• Customer references are available
• The instrument will be fully functional!
• Smooth process from the initial quote to order fulfillment

This will ship via freight. Please contact us with your zip code to obtain a shipping quote.

PLEASE NOTE THAT THE QUESTIONS BELOW ARE ANSWERED IN MORE THOROUGH DETAIL ON OUR WEBSITE

Q: Can I view this instrument in person at your facility or do a live Zoom demo before it is shipped to me?
A: We can accommodate both in-person or Zoom demos.

Q: What about the warranty?
A: The instrument comes fully warranted for both parts and labor.

Q: Do you offer installation, service, etc?
A: We offer remote installation and training packages to familiarize you with this instrument.

Q: What should I watch out for when buying a used/pre-owned instrument from another lab?
A: Ensure that the instrument is in good working condition with no damage or wear that could affect its performance. Ask for details about testing steps performed, video demo, and test screenshots.

Q: Do you have more than one of these instruments on hand?
A: We generally carry multiple instruments on hand, along with a variety of spare parts.

Q: This procurement is for a University or College. Are purchase orders with NET terms accepted?
A: We accept purchase orders from all major US and Canadian universities.

Q: How fast will you ship?
A: We can ship within a few days to two weeks. Shipping time depends on the current demand for our instruments. Members of our sales team will be able to offer current delivery estimates.

Q: Will my instrument be insured during shipping?
A: Absolutely! We insure all our shipments as long as we are the shipper.  If a customer ships on their account, they handle insurance.

Q: How do you pack? Have you previously packed and shipped the fragile laboratory instruments?
A: We have extensive experience shipping high-end and complex laboratory instruments in the US and Internationally.  

Q: Do you ship Internationally?
A: Yes! We have shipped to multiple continents and over 30 countries. 

Q: How much will I save buying it pre-owned, and is it worth it?
A: When compared to buying a new instrument, you will save 60% or more and have plenty of funds left over for an additional instrument or two.