For Sale Teledyne ISCO CombiFlash EZ Prep UV-VIS Preparative Flash Chromatography System 

Internal part number SM101682-UV-VIS

• Fully Functional
• Serviced & in Stock
• Current Model
• Good cosmetic condition
• Technical sales consultation available
• 60 DAYS INTERNATIONAL WARRANTY
• Includes remote instrument setup and training session 

Here is what you will receive: 

• Teledyne ISCO CombiFlash EZ Prep UV/VIS System
• Intake hoses with caps and solvent filters (Qty.:4)
• Set of waste hoses
• Collection Racks (Qty.:2) (please inquire for available inventory to match the collection tubes you are using)
• Column bypass tube
• Power cable
• Kindly note: Glassware, test tubes, and columns are not included.
• You can purchase different-sized racks from Teledyne, or if we have them in stock, they can be swapped out.

CombiFlash EZ Prep UV-VIS Flash Chromatography System Configuration:

• Flow rate range: 5-200mL/min
• Flow Rate Accuracy: /- 5%
• Maximum Pressure (high-pressure operation): up to 3500 psi (240 bar)
• Maximum Pressure (flash operation): 200 psi (13.8 bar)
• Ambient Temperature: 20 to 40 DegC
• Number of Solvents: binary gradient between any two of the four solvents
• Programmable Gradients: Linear, step, isocratic
• Gradient Accuracy: /-3%
• UV-Vis Detection Wavelength: 200 to 800 nm, in /-5 nm increments
• Dimensions (W x D x H): 17 x 17.0 x 26.5 in (43 x 43 x 67 cm)
• Weight: 37.4 kg (82.5 lbs.)
• Power requirements: 100-240VAC 50/60Hz

Customization/Options: 

• We carry a variety of racks, solid load caps, and other accessories. Please inquire with us for availability.
• Used untested Columns (please inquire for available inventory; we have an assortment of columns available and can include one at no charge)
• New Columns (please inquire for available inventory; we occasionally have new columns on hand)

Testing performed by our in-house service team:

The CombiFlash EZ Prep UV-VIS Flash Chromatography System passed all tests and was found to be fully functional:

• We verified the power supply and initialization.
• We calibrated the touch screen interface.
• We assessed the accuracy of arm movement.
• We confirmed the RFID column detection.
• We evaluated the waste and source-level sensing.
• We clean and inspect the check valves.
• We tested the manual control functionality.
• We checked the HPLC prime operation for consistency.
• We analyzed the gradient performance.
• We verified the UV detection using a sodium iodide solution.
• We perform the PHE/N-BBZ test to confirm correct gradient behavior.

Instrument Overview:

• Teledyne ISCO CombiFlash EZ Prep UV-VIS Preparative Flash Chromatography System integrates prep-scale flash and HPLC modes.
• Equipped with dual piston pumps for high-precision gradient control across wide flow-rate ranges.
• UV-VIS detector covers multiple wavelengths, enabling selective detection and accurate fraction triggering.
• Supports loading of crude mixtures from milligrams up to tens of grams with high recovery rates.
• Pressure-rated hardware accommodates high backpressures for rapid purification of diverse compounds.
• The system enhances efficiency in laboratories focused on organic synthesis and compound isolation.

Instrument Application:

• Purification of synthetic organic compounds after reaction steps
• Isolation of natural products from plant or microbial extracts
• Scale-up of lead molecules for medicinal chemistry studies
• Separation of closely related analogs or isomers for characterization

The Key Features:

• Integrated flash chromatography and preparative HPLC modes
• Dual piston gradient pumps with programmable flow rates
• UV-VIS detector covering a wide wavelength range
• Fraction collector module (standard rack, limited capacity)
• Software interface for instrument control and basic data handling

WHY DO CUSTOMERS MAKING CRITICAL LAB PURCHASES CHOOSE TO ORDER CHROMATOGRAPHY SYSTEMS FROM US?

They want to ensure all pump heads, seals, and check valves have been tested for consistent pressure generation and stable flow rates, preventing gradient drift, pulsation, or baseline instability.

They want peace of mind knowing the system has been fully flushed, primed, and run through gradient and collection tests under realistic purification conditions.

They want to ensure expected retention times for verification standards fall within tolerance, confirming that solvent routing, column integrity, and pump calibration are functioning within manufacturer specifications.

They want to avoid baseline instability, incorrect solvent mixing, or poor fraction resolution caused by untested pumps, misconfigured detectors, or software timing errors, issues that often go undetected until critical purification work is lost.

They want assurance that fraction collectors, diverter valves, and switching modules operate correctly under pressure and respond precisely to signal triggers, avoiding miscollection or cross-fraction contamination.

They want to ensure the UV lamp has been checked for remaining life and replaced if needed, so the system generates good data and is ready to use the same day it is installed.

They want peace of mind, knowing their instrument is backed by a warranty from a company that can stand behind it.

Our Advantage

• We have experience servicing and repairing these instruments.
• This instrument goes through all the described service steps before shipping.  see the questions section below  
• We offer detailed photos and videos of the instruments you buy.
• We are an approved pre-owned equipment vendor to many large US, Canadian, and EU Universities.
• We are an approved pre-owned equipment vendor to many Fortune 500 US and International Biopharma companies. 
• Technical sales consultation available
• Remote installation and instrument operation training may be available.
• On-site installation may be available in the Boston Area (New England area)
• US or International shipping is no problem (see the shipping tab on how we pack and feel at ease)

Our Guarantee

• Warranty
• An extended warranty may be available
• You get after-sales technical support
• Customer references are available
• The instrument will be fully functional!
• Smooth process from the initial quote to order fulfillment

This will ship via freight. Please contact us with your zip code to obtain a shipping quote.

SM Small Crate
225#

PLEASE NOTE THAT THE QUESTIONS BELOW ARE ANSWERED IN MORE THOROUGH DETAIL ON OUR WEBSITE

Q: Can I view this instrument in person at your facility or do a live Zoom demo before it is shipped to me?
A: We can accommodate both in-person or Zoom demos.

Q: What about the warranty?
A: The instrument comes fully warranted for both parts and labor.

Q: Do you offer installation, service, etc?
A: We offer remote installation and training packages to familiarize you with this instrument.

Q: What should I watch out for when buying a used/pre-owned instrument from another lab?
A: Ensure that the instrument is in good working condition with no damage or wear that could affect its performance. Ask for details about testing steps performed, video demo, and test screenshots.

Q: Do you have more than one of these instruments on hand?
A: We generally carry multiple instruments on hand, along with a variety of spare parts.

Q: This procurement is for a University or College. Are purchase orders with NET terms accepted?
A: We accept purchase orders from all major US and Canadian universities.

Q: How fast will you ship?
A: We can ship within a few days to two weeks. Shipping time depends on the current demand for our instruments. Members of our sales team will be able to offer current delivery estimates.

Q: Will my instrument be insured during shipping?
A: Absolutely! We insure all our shipments as long as we are the shipper.  If a customer ships on their account, they handle insurance.

Q: How do you pack? Have you previously packed and shipped the fragile laboratory instruments?
A: We have extensive experience shipping high-end and complex laboratory instruments in the US and Internationally.  

Q: Do you ship Internationally?
A: Yes! We have shipped to multiple continents and over 30 countries. 

Q: How much will I save buying it pre-owned, and is it worth it?
A: When compared to buying a new instrument, you will save 60% or more and have plenty of funds left over for an additional instrument or two.